Douamba Zoenabo, Bisseye Cyrille, Djigma Florencia W, Compaoré Tegwinde R, Bazie Valérie Jean Telesphore, Pietra Virginio, Nikiema Jean-Baptiste, Simpore Jacques
Biomolecular Research Center Pietro Annigoni-CERBA, Labiogene, UFR/SVT, University of Ouagadougou, 01BP364 Ouagadougou 01, Burkina Faso.
J Biomed Biotechnol. 2012;2012:198317. doi: 10.1155/2012/198317. Epub 2012 Nov 11.
Sub-Saharan Africa records each year about thirty-two million pregnant women living in areas of high transmission of Plasmodium falciparum causing malaria. The aim of this study was to carve out the prevalence of asymptomatic malaria among pregnant women and to emphasize its influence on haematological markers. The prevalence of Plasmodium falciparum asymptomatic infection among pregnant women was 30% and 24% with rapid detection test (RDT) and microscopy, respectively. The prevalence of P. falciparum asymptomatic malaria was reduced among pregnant women using sulfadoxine-pyrimethamine's intermittent preventive treatment and 61% of them were anaemic. Anaemia was significantly more common in women infected with P. falciparum compared with the uninfected pregnant women. Most of the women had normal levels of homocysteine and low levels of folate, respectively. Therefore, the systematic diagnosis of malaria should be introduced to pregnant women as a part of the antenatal care.
撒哈拉以南非洲地区每年记录约有3200万孕妇生活在恶性疟原虫传播高发地区，这种疟原虫会引发疟疾。本研究的目的是查明孕妇中无症状疟疾的患病率，并强调其对血液学指标的影响。孕妇中恶性疟原虫无症状感染的患病率，通过快速检测试验（RDT）和显微镜检查分别为30%和24%。使用磺胺多辛-乙胺嘧啶进行间歇性预防治疗的孕妇中，恶性疟原虫无症状疟疾的患病率有所降低，其中61%的孕妇贫血。与未感染的孕妇相比，感染恶性疟原虫的女性贫血明显更为常见。大多数女性的同型半胱氨酸水平正常，叶酸水平较低。因此，应将疟疾的系统诊断作为产前护理的一部分引入孕妇群体。
