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惯性沉积效应:利用激光多普勒测速仪和荧光染料对气管中的气溶胶力学进行的一项研究。

Inertial deposition effects: a study of aerosol mechanics in the trachea using laser Doppler velocimetry and fluorescent dye.

作者信息

Corcoran T E, Chigier Norman

机构信息

University of Pittsburgh, Pittsburgh, PA, USA.

出版信息

J Biomech Eng. 2002 Dec;124(6):629-37. doi: 10.1115/1.1516572.

Abstract

This study characterizes the axial velocity and axial turbulence intensity patterns noted in the tracheal portion of a cadaver-based throat model at two different steady flow rates (18.1 and 41.1 LPM.) This characterization was performed using Phase Doppler Interferometry (Laser Doppler Velocimetry). Deposition, as assessed qualitatively using fluorescent dye, is related to the position of the laryngeal jet within the trachea. The position of the jet is dependent on the downstream conditions of the model. It is proposed therefore that lung/airway conditions may have important effects on aerosol deposition within the throat. There is no correspondence noted between regions of high axial turbulence intensity and deposition.

摘要

本研究描述了在基于尸体的喉部模型的气管部分,于两种不同稳定流速(18.1和41.1升/分钟)下所观察到的轴向速度和轴向湍流强度模式。这种描述是使用相位多普勒干涉测量法(激光多普勒测速法)进行的。使用荧光染料定性评估的沉积与气管内喉喷射流的位置有关。喷射流的位置取决于模型的下游条件。因此,有人提出肺部/气道状况可能对喉部内的气溶胶沉积有重要影响。在高轴向湍流强度区域和沉积之间未发现对应关系。

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