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PALM技术：兔角膜遮盖式光治疗性角膜切削术的组织学结果

The PALM Technique: histological findings of masked phototherapeutic keratectomy on rabbit corneas.

作者信息

Katsanevaki Vikentia J, Ginis Harilaos S, Naoumidi Irini I, Pallikaris Ioannis G

机构信息

University of Crete, Medical School, Vardinoyannion Eye Institute of Crete, Heraklion, Crete, Greece.

出版信息

BMC Ophthalmol. 2003 Feb 19;3:4. doi: 10.1186/1471-2415-3-4.

DOI:10.1186/1471-2415-3-4
PMID:12597779
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC151685/
Abstract

BACKGROUND

To compare the corneal healing response between conventional and phototherapeutic keratectomy through a masking agent, in rabbit corneas.

METHODS

24 adult rabbits underwent phototherapeutic keratectomy. Animals were divided in two groups: 12 received photoablation through a masking agent (PALM gel) and the remaining 12 received conventional phototherapeutic keratectomy of equal depth and served as control. Light and transmission electron microscopy was performed in specimens of both groups obtained: immediately after, four hours, one week, one, three and six months after treatment.

RESULTS

Reepitheliazation was complete within five days in all eyes. Light and transmission electron microscopy did not reveal any differences of the healing process in the experimental eyes compared to the controls.

CONCLUSION

Photoablation through the PALM technique did not result any evident alterations of the reepithelisation and stromal healing process.

摘要

背景

在兔角膜中，比较通过一种遮蔽剂进行的传统光治疗性角膜切削术与光治疗性角膜切削术之间的角膜愈合反应。

方法

24只成年兔接受了光治疗性角膜切削术。动物被分为两组：12只通过一种遮蔽剂（PALM凝胶）接受光消融，其余12只接受相同深度的传统光治疗性角膜切削术并作为对照。对两组获取的标本进行光镜和透射电镜检查：治疗后即刻、4小时、1周、1个月、3个月和6个月。

结果

所有眼睛在5天内上皮化完成。光镜和透射电镜检查显示，与对照组相比，实验眼的愈合过程没有任何差异。

结论

通过PALM技术进行的光消融没有导致上皮化和基质愈合过程出现任何明显改变。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2738/151685/e4e0278d7207/1471-2415-3-4-9.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2738/151685/e53fce3f3c1d/1471-2415-3-4-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2738/151685/4b8171f9176e/1471-2415-3-4-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2738/151685/328391ffe91b/1471-2415-3-4-3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2738/151685/aea132353958/1471-2415-3-4-4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2738/151685/8890856ee389/1471-2415-3-4-5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2738/151685/5d3cb30b5fa7/1471-2415-3-4-6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2738/151685/92f3101fc7e8/1471-2415-3-4-7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2738/151685/fb6b5c0e7a69/1471-2415-3-4-8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2738/151685/e4e0278d7207/1471-2415-3-4-9.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2738/151685/e53fce3f3c1d/1471-2415-3-4-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2738/151685/4b8171f9176e/1471-2415-3-4-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2738/151685/328391ffe91b/1471-2415-3-4-3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2738/151685/aea132353958/1471-2415-3-4-4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2738/151685/8890856ee389/1471-2415-3-4-5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2738/151685/5d3cb30b5fa7/1471-2415-3-4-6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2738/151685/92f3101fc7e8/1471-2415-3-4-7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2738/151685/fb6b5c0e7a69/1471-2415-3-4-8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2738/151685/e4e0278d7207/1471-2415-3-4-9.jpg

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本文引用的文献

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Treatment of corneal surface irregularities using biomask as an adjunct to excimer laser phototherapeutic keratectomy.
Cornea. 2002 Jan;21(1):28-32. doi: 10.1097/00003226-200201000-00007.
2
Correction of irregular astigmatism with excimer laser assisted by sodium hyaluronate.透明质酸钠辅助准分子激光矫正不规则散光
Ophthalmology. 2001 Jul;108(7):1246-60. doi: 10.1016/s0161-6420(01)00602-9.
3
Refractive changes after excimer laser phototherapeutic keratectomy.准分子激光角膜切削术后的屈光变化。
J Cataract Refract Surg. 2001 May;27(5):686-92. doi: 10.1016/s0886-3350(01)00802-1.
4
The BioMask for treatment of corneal surface irregularities with excimer laser phototherapeutic keratectomy.用于准分子激光角膜切削术治疗角膜表面不规则的生物面罩。
Cornea. 1999 Mar;18(2):155-63. doi: 10.1097/00003226-199903000-00003.
5
Histopathology of corneal wound healing after photorefractive keratectomy in rabbit eyes.兔眼准分子激光原位角膜磨镶术后角膜伤口愈合的组织病理学研究
J Refract Surg. 1998 Apr;14(2 Suppl):S209-11. doi: 10.3928/1081-597X-19980401-15.
6
Molecular cell biology for the refractive corneal surgeon: programmed cell death and wound healing.屈光角膜手术医生的分子细胞生物学：程序性细胞死亡与伤口愈合
J Refract Surg. 1997 Mar-Apr;13(2):171-5. doi: 10.3928/1081-597X-19970301-15.
7
Histopathological comparison of photorefractive keratectomy and laser in situ keratomileusis in rabbits.兔眼准分子激光角膜切削术与准分子激光原位角膜磨镶术的组织病理学比较
J Refract Surg. 1996 Nov-Dec;12(7):758-66. doi: 10.3928/1081-597X-19961101-07.
8
Changes in descemet membrane and endothelium after corneal epithelial abrasion alone and with photorefractive keratectomy in rabbits.
Arch Ophthalmol. 1996 Sep;114(9):1105-8. doi: 10.1001/archopht.1996.01100140307009.
9
Phototherapeutic keratectomy: strategies and results in 12 eyes.光治疗性角膜切削术：12 只眼的治疗策略与结果
Refract Corneal Surg. 1993 Mar-Apr;9(2 Suppl):S90-5.
10
Phototherapeutic keratectomy: long-term results in 166 eyes.光治疗性角膜切削术：166只眼的长期结果
Refract Corneal Surg. 1993 Mar-Apr;9(2 Suppl):S76-81.