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光治疗性角膜切削术:12 只眼的治疗策略与结果

Phototherapeutic keratectomy: strategies and results in 12 eyes.

作者信息

Hersh P S, Spinak A, Garrana R, Mayers M

机构信息

Department of Ophthalmology, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, NY 10467.

出版信息

Refract Corneal Surg. 1993 Mar-Apr;9(2 Suppl):S90-5.

PMID:8499388
Abstract

As part of a multicenter study of excimer laser procedures, we performed phototherapeutic keratectomy (PTK) on 12 eyes in 11 patients. Three eyes had superficial corneal scarring, two Salzmann's degeneration, two Reis-Bückler's dystrophy; and one each with recurrent lattice dystrophy in a corneal graft, band keratopathy, recurrent erosion syndrome, after pterygium scarring, and contact-lens related keratopathy. Indications for treatment included poor visual acuity, severe glare symptoms, ocular surface discomfort, recurrent erosions, and monocular diplopia. Follow up ranged from 1 to 4 months. Best spectacle corrected visual acuity improved in ten eyes with no eyes suffering loss of best spectacle corrected visual acuity. A hyperopic refractive shift was found in eight of 12 treated eyes. Corneal surface regularity improved in six of 12 eyes and worsened in one eye as measured by computerized corneal topographic analysis. Ten patients (11 eyes) noted improvement in their visual perception and subjective symptoms. We review various strategies of phototherapeutic keratectomy designed to treat particular corneal disorders: patient selection criteria to optimize clinical outcome are reviewed as well.

摘要

作为一项准分子激光手术多中心研究的一部分,我们对11例患者的12只眼实施了光治疗性角膜切削术(PTK)。其中3只眼有浅层角膜瘢痕,2只眼有萨尔茨曼变性,2只眼有 Reis-Bückler营养不良;另外1只眼分别患有角膜移植术后复发性格子状营养不良、带状角膜病变、复发性糜烂综合征、翼状胬肉瘢痕形成后以及与隐形眼镜相关的角膜病变。治疗指征包括视力差、严重眩光症状、眼表不适、复发性糜烂和单眼复视。随访时间为1至4个月。10只眼的最佳矫正视力得到改善,没有眼的最佳矫正视力下降。12只接受治疗的眼中有8只出现远视性屈光偏移。通过计算机化角膜地形图分析测量,12只眼中有6只角膜表面规则性改善,1只眼恶化。10例患者(11只眼)的视觉感知和主观症状有改善。我们回顾了旨在治疗特定角膜疾病的光治疗性角膜切削术的各种策略:还回顾了优化临床结果的患者选择标准。

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