Dosdá Rosa, Martí-Bonmatí Luis, Ronchera-Oms Crisanto L, Mollá Enrique, Arana Estanislao
Department of Radiology, Clínica Quirón, Avda. Blasco Ibañez, 14, 46017 Valencia, Spain.
Eur Radiol. 2003 Feb;13(2):294-8. doi: 10.1007/s00330-002-1500-5. Epub 2002 Jun 21.
In abdominal MR imaging, ghost artifacts from noncyclic bowel movements can reduce the quality of the images. Although pharmacologic suppression of motion is effective, no study has being conducted to analyze the influence of drug motion suppression on fast breath-hold 1.5-T examinations of the upper abdomen. A prospective, randomized, double-blind trial was conducted in 50 patients. Patients were randomly distributed into two groups: The control group received only an oral solution, whereas the other group received the oral solution plus a subcutaneous injection of 20 mg of butylscopolamine 10 min before the MR examination. Breath-hold T1-weighted gradient-recalled-echo (GRE) MR images were obtained in a 1.5-T superconductive unit. Quantitative image analysis was performed with region-of-interest (ROI) measurements of the signal intensity of the liver and in background air anterior and lateral to the patient. A qualitative analysis of the subjective quality of the T1-weighted images was also done, and the adverse reactions were registered. The groups were homogeneous regarding age, gender, and weight distribution. No significant differences in the signal intensity of the liver and in the incoherent noise measurements were found between the two groups. Gastrointestinal noise showed significant differences between groups, with lower values for the butylscopolamine group compared with the control group. There was also a statistically significant difference in the image quality between groups, and optimal studies were only found in the butylscopolamine group, where most patients had a good-quality evaluation. Regarding adverse events, there were non-significant differences between groups. In conclusion, administration of an antiperistaltic agent to reduce the movements of the gastrointestinal tract diminishes the motion artifacts generated on MR imaging of the abdomen, even at high field strength and with fast imaging sequences. Images of the upper abdomen obtained after pharmacologic suppression of the gastrointestinal movement are of significantly superior quality.
在腹部磁共振成像中，非周期性肠道蠕动产生的鬼影伪影会降低图像质量。尽管药物抑制运动有效，但尚未有研究分析药物运动抑制对上腹部快速屏气1.5-T检查的影响。对50例患者进行了一项前瞻性、随机、双盲试验。患者被随机分为两组：对照组仅接受口服溶液，而另一组在磁共振检查前10分钟接受口服溶液加皮下注射20毫克丁溴东莨菪碱。在1.5-T超导设备中获取屏气T1加权梯度回波（GRE）磁共振图像。通过对肝脏信号强度以及患者前方和侧面背景空气进行感兴趣区域（ROI）测量来进行定量图像分析。还对T1加权图像的主观质量进行了定性分析，并记录了不良反应。两组在年龄、性别和体重分布方面具有同质性。两组之间在肝脏信号强度和非相干噪声测量方面未发现显著差异。胃肠道噪声在两组之间显示出显著差异，丁溴东莨菪碱组的值低于对照组。两组之间在图像质量上也存在统计学显著差异，仅在丁溴东莨菪碱组中发现了最佳研究结果，该组大多数患者的评估质量良好。关于不良事件，两组之间无显著差异。总之，给予抗蠕动药物以减少胃肠道运动可减少腹部磁共振成像中产生的运动伪影，即使在高场强和快速成像序列下也是如此。药物抑制胃肠道运动后获得的上腹部图像质量明显更优。
