Roethke Matthias C, Kuru Timur H, Radbruch Alexander, Hadaschik Boris, Schlemmer Heinz-Peter
Matthias C Roethke, Alexander Radbruch, Heinz-Peter Schlemmer, Department of Radiology, German Cancer Research Center Heidelberg (DKFZ), 69120 Heidelberg, Germany.
World J Radiol. 2013 Jul 28;5(7):259-63. doi: 10.4329/wjr.v5.i7.259.
To evaluate the value of administration of hyoscine-N-butyl-bromide (HBB) for image quality magnetic resonance imaging (MRI) of the prostate.
Seventy patients were retrospectively included in the study. Thirty-five patients were examined with administration of 40 milligrams of HBB (Buscopan(®); Boehringer, Ingelheim, Germany); 35 patients were examined without HBB. A multiparametric MRI protocol was performed on a 3.0 Tesla scanner without using an endorectal coil. The following criteria were evaluated independently by two experienced radiologists on a five-point Likert scale: anatomical details (delineation between peripheral and transitional zone of the prostate, visualisation of the capsule, depiction of the neurovascular bundles); visualisation of lymph nodes; motion related artefacts; and overall image quality.
Comparison of anatomical details between the two cohorts showed no statistically significant difference (3.9 ± 0.7 vs 4.0 ± 0.9, P = 0.54, and 3.8 ± 0.7 vs 4.2 ± 0.6, P = 0.07) for both readers. There was no significant advantage regarding depiction of local and iliac lymph nodes (3.9 ± 0.6 vs 4.2 ± 0.6, P = 0.07, and 3.8 ± 0.9 vs 4.1 ± 0.8, P = 0.19). Motion artefacts were rated as "none" to "few" in both groups and showed no statistical difference (2.3 ± 1.0 vs 1.9 ± 0.9, P = 0.19, and 2.3 ± 1.1 vs 1.9 ± 0.7, P = 0.22). Overall image quality was rated "good" in average for both cohorts without significant difference (4.0 ± 0.6 vs 4.0 ± 0.9, P = 0.78, and 3.8 ± 0.8 vs 4.2 ± 0.6, P = 0.09).
The results demonstrated no significant effect of HBB administration on image quality. The study suggests that use of HBB is not mandatory for MRI of the prostate at 3.0 Tesla.
评估丁溴东莨菪碱（HBB）给药对前列腺磁共振成像（MRI）图像质量的价值。
回顾性纳入70例患者。35例患者在给予40毫克HBB（消旋山莨菪碱；德国勃林格殷格翰公司）后进行检查；35例患者未使用HBB进行检查。在一台3.0特斯拉扫描仪上执行多参数MRI方案，不使用直肠内线圈。由两名经验丰富的放射科医生独立采用五点李克特量表对以下标准进行评估：解剖细节（前列腺外周带和移行带之间的界限、包膜的可视化、神经血管束的描绘）；淋巴结的可视化；运动相关伪影；以及整体图像质量。
两个队列之间的解剖细节比较显示，两位阅片者的结果均无统计学显著差异（3.9±0.7对4.0±0.9，P = 0.54；3.8±0.7对4.2±0.6，P = 0.07）。在局部和髂淋巴结的描绘方面没有显著优势（3.9±0.6对4.2±0.6，P = 0.07；3.8±0.9对4.1±0.8，P = 0.19）。两组的运动伪影均被评为“无”至“少”，且无统计学差异（2.3±1.0对1.9±0.9，P = 0.19；2.3±1.1对1.9±0.7，P = 0.22）。两个队列的整体图像质量平均评为“良好”，无显著差异（4.0±0.6对4.0±0.9，P = 0.78；3.8±0.8对4.2±0.6，P = 0.09）。
结果表明HBB给药对图像质量无显著影响。该研究表明，在3.0特斯拉进行前列腺MRI时，使用HBB并非必需。
