Wiśniewski K, Buczko W, Moniuszko-Jakoniuk J
Acta Neurobiol Exp (Wars). 1975;35(3):275-83.
Low molecular peptides, derived from fibrinogen digested by plasmin and injected either intraperitoneally or into the brain lateral ventricle, were found to act depressively on the CNS in active rats, while in fairly active rats they showed stimulatory effects. Fractionation of P-FDP on Sephadex G-25 showed that the most active peptides had a molecular weight lower than 5,000.
纤溶酶消化纤维蛋白原得到的低分子肽，经腹腔注射或注入脑侧脑室后，发现在活跃大鼠中对中枢神经系统有抑制作用，而在相当活跃的大鼠中则表现出刺激作用。在葡聚糖凝胶G - 25上对P - FDP进行分级分离表明，活性最强的肽分子量低于5000。
