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Acquired XO/XY clones in bone marrow of a patient with paroxysmal nocturnal hemoglobinuria (PNH).

作者信息

Whang-Peng J, Knutsen T, Lee E C, Leventhal B

出版信息

Blood. 1976 Apr;47(4):611-9.

PMID:1260124
Abstract

Cytogenetic studies showed both 45XO and 46XY clones in the bone marrow of a 76-yr-old male with a 17-yr history of paroxysmal nocturnal hemoglobinuria (PNH). 55Fe incorporation studies demonstrated that both clones involved the hematopoietic stem cells. The loss of the Y chromosome may reflect an aging phenomenon, rather than be related to the PNH.

摘要

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