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通过钕钇铝石榴石激光熔覆获得的磷酸钙涂层:物理化学和生物学特性。

Calcium phosphate coatings obtained by Nd:YAG laser cladding: physicochemical and biologic properties.

作者信息

Lusquiños F, De Carlos A, Pou J, Arias J L, Boutinguiza M, León B, Pérez-Amor M, Driessens F C M, Hing K, Gibson I, Best S, Bonfield W

机构信息

Dpto. Física Aplicada, Universidade de Vigo, Vigo, Spain.

出版信息

J Biomed Mater Res A. 2003 Mar 15;64(4):630-7. doi: 10.1002/jbm.a.10440.

DOI:10.1002/jbm.a.10440
PMID:12601774
Abstract

The plasma spray (PS) technique is the most popular method commercially in use to produce calcium phosphate (CaP) coatings to promote fixation and osteointegration of the cementless prosthesis. Nevertheless, PS has some disadvantages, such as the poor coating-to-substrate adhesion, low mechanical strength, and brittleness of the coating. In order to overcome the drawbacks of plasma spraying, we introduce in this work a new method to apply a CaP coating on a Ti alloy using a well-known technique in the metallurgical field: laser surface cladding. The physicochemical characterization of the coatings has been carried out by means of X-ray diffraction (XRD), scanning electron microscopy (SEM), and energy dispersive X-ray analysis (EDX). The biologic properties of the coatings have been assessed in vitro with human osteoblast-like MG-63 cells. The overall results of this study affirm that the Nd:YAG laser cladding technique is a promising method in the biomedical field.

摘要

等离子喷涂(PS)技术是目前商业上最常用的生产磷酸钙(CaP)涂层的方法,用于促进非骨水泥假体的固定和骨整合。然而,PS存在一些缺点,如涂层与基体的附着力差、机械强度低以及涂层的脆性。为了克服等离子喷涂的缺点,我们在这项工作中引入了一种在冶金领域广为人知的技术:激光表面熔覆,在钛合金上涂覆CaP涂层的新方法。通过X射线衍射(XRD)、扫描电子显微镜(SEM)和能量色散X射线分析(EDX)对涂层进行了物理化学表征。用人类成骨样MG-63细胞在体外评估了涂层的生物学特性。这项研究的总体结果证实,Nd:YAG激光熔覆技术在生物医学领域是一种很有前景的方法。

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