Krauze-Baranowska Miroslawa
Department of Pharmacognosy, Medical University of Gdańsk, 107 Gen. J. Hallera Str., 80-416 Gdańsk, Poland.
Acta Pol Pharm. 2002 Sep-Oct;59(5):403-10.
For some years now there has been a systematic increase in the number of reports on new secondary metaholites of truxillic and truxinic acid derivatives. The paper offers a presentation of existing forms of cyclobutanodicarhoxylic acids in plant kingdom. while considering their stereochemical structure and hiosynthesis. Also presented are some results of research on the pharmacological activity of synthetic and natural derivatives of these compounds. The paper shows additionally the results of search in nature for compounds containing fragments of truxillic and truxinic acids seen against the occurrence of other compounds of cyclobutane derivatives in plant kingdom.
近年来，关于吐昔酸和吐昔宁酸衍生物新的次生代谢产物的报道数量一直在系统性增加。本文介绍了植物界中环丁烷二甲酸的现有形式，同时考虑了它们的立体化学结构和生物合成。还介绍了这些化合物的合成和天然衍生物药理活性的一些研究结果。本文还展示了在自然界中寻找含有吐昔酸和吐昔宁酸片段的化合物的研究结果，这是相对于植物界中其他环丁烷衍生物化合物的出现情况而言的。
