Sagawa Takaaki, Takaishi Yoshihisa, Fujimoto Yoshinori, Duque Carmenza, Osorio Coralia, Ramos Freddy, Garzon Cristina, Sato Mitsunobu, Okamoto Masato, Oshikawa Tetsuya, Ahmed Sharif Uddin
Graduate School of Pharmaceutical Sciences, University of Tokushima, Sho-machi, Tokushima 770-8505, Japan.
J Nat Prod. 2005 Apr;68(4):502-5. doi: 10.1021/np040187y.
Five cyclobutane dimers, achyrodimers A-E (1-5), along with 11 known compounds were isolated from the methanol extract of the Colombian medicinal plant Achyrocline bogotensis. Their structures were elucidated by spectroscopy. Several of these compounds were screened for cytokine-inducing activity in human peripheral blood mononuclear cells.
从哥伦比亚药用植物波哥大牛膝菊的甲醇提取物中分离出5种环丁烷二聚体，即牛膝菊二聚体A - E（1 - 5），以及11种已知化合物。通过光谱学对它们的结构进行了阐明。对其中几种化合物进行了人外周血单核细胞中细胞因子诱导活性的筛选。
