Metz J, Metz G
Arch Dermatol Forsch. 1975 Jul 18;252(4):285-96.
Electronmicroscopical investigation on 12 cutaneous biopsies of different localisation showed that the seborrhoic dermatitis is not comparable to a psoriatic tissue-reaction. Both, the cyto-morphological feature and the demonstrated localisation of the acid phosphatase are distinctly different from that of the psoriatic epidermis. The described changes are clearly more similar to the well known ultrastructural pictures of eczemateous reactions. In spite of the "eczema-like" ultrastructural picture seborrhoic dermatitis apparently can be separated from the allergic and irritant contact-dermatitis. Nevertheless, the epidermal alterations are also similar to chronic nummular eczema. They therefore are unspecific and do not allow any conclusion regarding the etiopathogenesis or nosological classification of this skin disease.
对12例不同部位皮肤活检标本进行的电子显微镜检查表明，脂溢性皮炎与银屑病的组织反应不同。其细胞形态学特征以及所显示的酸性磷酸酶定位均与银屑病表皮明显不同。所描述的变化显然更类似于众所周知的湿疹样反应的超微结构图像。尽管脂溢性皮炎有“湿疹样”超微结构图像，但它显然可与过敏性和刺激性接触性皮炎相区分。然而，其表皮改变也与慢性钱币状湿疹相似。因此，这些改变是非特异性的，无法对这种皮肤病的病因发病机制或疾病分类得出任何结论。
