Tsuda H, Fukushima S, Takahashi M, Hikosaka Y, Hayashi K
Cancer. 1976 Apr;37(4):1831-9. doi: 10.1002/1097-0142(197604)37:4<1831::aid-cncr2820370430>3.0.co;2-v.
This paper describes an unusual, familial bilateral papillary cystadenoma of the epididymis found in three siblings. The histological characteristics of the tumor were: 1) papillary proliferation of clear cells, consisting of both tall columnar and round ovoid cells, in the efferent duct epithelium; and 2) cystic dilatation of the duct with colloidal material. The present cases were unique in two respects: 1) familial bilateral papillary cystadenomas probably associated with Lindau's disease have not been reported previously: and 2) electron microscopic observations suggested that the tumors originated from the efferent duct.
