Giessing M, Deger S, Ebeling V, Roigas J, Türk I, Loening S A
Universitätsklinik für Urologie, Charité, Berlin.
Urologe A. 2003 Feb;42(2):218-24. doi: 10.1007/s00120-002-0281-4. Epub 2003 Feb 22.
Living donor kidney transplantation is one possibility to meet the growing demand for organs in patients with chronic renal failure. In 1995 the first laparoscopic living donor nephrectomy (LDN) was performed in the United States. More than 100 transplant centers worldwide perform LDN. The expectations of a larger number of willing organ donors were fulfilled due to the less traumatic operation. Meanwhile, several techniques exist to retrieve a kidney laparoscopically, including the trans- or retroperitoneal, strictly laparoscopic, or hand-assisted approach. From February 1999 to September 2002, 63 strictly laparoscopic, transperitoneal LDNs were performed at the Department of Urology of the Charité University Hospital, Berlin. Warm ischemic time was 148 s (105-360) and operating time was 203 min (110-305). Intraoperative complications were due to insufficient closure of the vessels in four patients. Mean postoperative hospital stay was 5.7 days (3-9). One year after LDN, renal function as well as creatinine levels of the recipient showed no difference compared to the organs harvested via the approach at our department prior to implementation of LDN. Strictly laparoscopic transperitoneal donor nephrectomy is a safe method for kidney retrieval and ensures excellent graft function.
活体供肾移植是满足慢性肾衰竭患者不断增长的器官需求的一种可能性。1995年,美国实施了首例腹腔镜活体供肾切除术(LDN)。全球有100多个移植中心开展LDN。由于手术创伤较小,大量潜在器官捐献者的期望得以实现。同时,存在多种腹腔镜取肾技术,包括经腹或腹膜后、单纯腹腔镜或手辅助入路。1999年2月至2002年9月,柏林夏里特大学医院泌尿外科实施了63例单纯腹腔镜经腹LDN。热缺血时间为148秒(105 - 360秒),手术时间为203分钟(110 - 305分钟)。4例患者术中并发症是由于血管闭合不充分。术后平均住院时间为5.7天(3 - 9天)。LDN术后1年,受者的肾功能以及肌酐水平与该科室在实施LDN之前通过其他入路获取的器官相比无差异。单纯腹腔镜经腹供肾切除术是一种安全的取肾方法,可确保良好的移植肾功能。