Unsicker K
Cell Tissue Res. 1976 Jan 28;165(4):477-508. doi: 10.1007/BF00224477.
Chromaffin, small granule-containing (SGC)-cells, neurons and the innervation of these cells was studied in the adrenal gland of three species of reptiles (Testudo graeca, Lacerta dugesi, Natrix natrix). 1. After fixation with glutaraldehyde and osmium-tetroxide adrenaline (A)- and noradrenaline (NA)-storing cells can be distinguished by means of the different electron density of their granules: A-granules are moderately electron-dense, while NA-granules show a core of high electron density. The unusually high electron density of a few A-granules in Testudo occasionally required viewing of unstained sections which facilitated the discrimination of the two cell types in this species. In all species studied NA-granules display a remarkable polymorphism which is most pronounced in the tortoise. In this species A-granules are polymorphic, too. Both types of granules show wide variations in size, which are particularly great in the tortoise. This species also exhibits the largest average sizes for A-granules (285 nm), and NA-granules (354 nm). The corresponding parameters for Lacerta and Natrix, are 255 and 179 nm for A- and 323 and 304 nm for NA-granules, respectively. The rough ER in A-cells of the tortoise regularly occurs in the form of circular dilations ('ergastosomes', Kanerva and Hervonen, 1973). Mitochondria sometimes contain longitudinal cristae with a crystalloid internal pattern. Large dense bodies which incorporate granules are abundant in NA-cells. Smaller dense bodies containing a few dense patches and membranes are present in both A- and NA-cells. Intermediate stages between dense bodies and what appear to be A- or NA-granules (if the latter have lost some of their amine-content) are frequently observed.
研究了三种爬行动物（希腊陆龟、杜氏蜥蜴、草游蛇）肾上腺中的嗜铬细胞、含小颗粒（SGC）细胞、神经元及其神经支配。1. 用戊二醛和四氧化锇固定后，可通过其颗粒不同的电子密度区分储存肾上腺素（A）和去甲肾上腺素（NA）的细胞：A颗粒电子密度中等，而NA颗粒显示高电子密度的核心。希腊陆龟中少数A颗粒异常高的电子密度偶尔需要观察未染色切片，这有助于区分该物种中的两种细胞类型。在所有研究的物种中，NA颗粒表现出显著的多态性，在乌龟中最为明显。在该物种中，A颗粒也具有多态性。两种类型的颗粒大小变化很大，在乌龟中尤为显著。该物种的A颗粒（285 nm）和NA颗粒（354 nm）的平均尺寸也最大。蜥蜴和草游蛇的相应参数分别为：A颗粒为255和179 nm，NA颗粒为323和304 nm。乌龟A细胞中的粗面内质网通常以圆形扩张（“动质体”，卡内尔瓦和赫尔沃宁于1973年提出）的形式出现。线粒体有时含有具有晶体内部模式的纵向嵴。在NA细胞中大量存在包含颗粒的大致密体。在A细胞和NA细胞中均存在含有少量致密斑块和膜的较小致密体。经常观察到致密体与似乎是A或NA颗粒（如果后者失去了一些胺含量）之间的中间阶段。
