Billaud Geneviève, Peny Stéphanie, Legay Vincent, Lina Bruno, Valette Martine
CNR Enterovirus et CNR Grippe (France sud), Laboratoire de Virologie des Hospices Civils de Lyon, UMR 5537, Domaine Rockefeller, 69373 Lyon Cedex 08, France.
J Virol Methods. 2003 Mar;108(2):223-8. doi: 10.1016/s0166-0934(03)00038-7.
Human enteroviruses and rhinoviruses are respiratory pathogens whose role in acute respiratory infection is underestimated due to the use of diagnostic procedures with poor sensitivity. To determine the prevalence of these two pathogens in the upper respiratory tract infections, a multiplex procedure was developed that both detect and differentiate rhinoviruses and enteroviruses. This sensitive procedure allowed the detection of both pathogens from archival material (nasal swabs) collected during the previous winters and differentiated rhinoviruses from enteroviruses. This procedure can be used to determine the role of these pathogens in mild or severe upper respiratory tract infections.
人肠道病毒和鼻病毒是呼吸道病原体，由于诊断方法敏感性较差，它们在急性呼吸道感染中的作用被低估。为了确定这两种病原体在上呼吸道感染中的流行情况，开发了一种多重检测方法，该方法既能检测又能区分鼻病毒和肠道病毒。这种灵敏的方法能够从之前冬季收集的存档材料（鼻拭子）中检测出这两种病原体，并区分鼻病毒和肠道病毒。该方法可用于确定这些病原体在轻度或重度上呼吸道感染中的作用。
