使用两种提议的定义对代谢综合征患病率进行的比较。

A comparison of the prevalence of the metabolic syndrome using two proposed definitions.

作者信息

Ford Earl S, Giles Wayne H

机构信息

Division of Environmental Hazards and Health Effects, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA.

出版信息

Diabetes Care. 2003 Mar;26(3):575-81. doi: 10.2337/diacare.26.3.575.

DOI:10.2337/diacare.26.3.575

PMID:12610004

Abstract

OBJECTIVE

To compare the prevalence of the metabolic syndrome using two definitions: one proposed by the Third Report of the National Cholesterol Education Program Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III [ATP III]) and one by the World Health Organization (WHO).

RESEARCH DESIGN AND METHODS

We used data from a nationally representative sample of the noninstitutionalized civilian population of the U.S. from the Third National Health and Nutrition Examination Survey, a cross-sectional health examination survey (1988-1994).

RESULTS

Among 8608 participants aged >or=20 years, the age-adjusted prevalence was 23.9% using the ATP III definition and 25.1% using the WHO definition. Among all participants, 86.2% were classified as either having or not having the metabolic syndrome under both definitions. Estimates differed substantially for some subgroups, however. For example, in African-American men, the WHO estimate was 24.9%, compared with the ATP III estimate of 16.5%.

CONCLUSIONS

A universally accepted definition of the metabolic syndrome is needed.

摘要

目的

使用两种定义比较代谢综合征的患病率：一种由美国国家胆固醇教育计划成人高胆固醇检测、评估和治疗专家小组第三次报告（成人治疗小组III [ATP III]）提出，另一种由世界卫生组织（WHO）提出。

研究设计与方法

我们使用了第三次全国健康和营养检查调查（一项横断面健康检查调查，1988 - 1994年）中美国非机构化平民人口具有全国代表性样本的数据。

结果

在8608名年龄≥20岁的参与者中，根据ATP III定义，年龄调整后的患病率为23.9%，根据WHO定义为25.1%。在所有参与者中，86.2%在两种定义下都被归类为患有或未患有代谢综合征。然而，某些亚组的估计值有很大差异。例如，在非裔美国男性中，WHO的估计值为24.9%，而ATP III的估计值为16.5%。