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新诊断2型糖尿病患者中代谢综合征及其危险因素的患病率——一项基于医院的横断面研究。

Prevalence of metabolic syndrome and its risk factors among newly diagnosed type 2 diabetes mellitus patients - A hospital-based cross-sectional study.

作者信息

Krishna S Teja Rama, Bahurupi Yogesh, Kant Ravi, Aggarwal Pradeep, Ajith Athulya V

机构信息

Department of Community and Family Medicine, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India.

Department of General Medicine, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India.

出版信息

J Family Med Prim Care. 2024 Aug;13(8):3325-3331. doi: 10.4103/jfmpc.jfmpc_51_24. Epub 2024 Jul 26.

Abstract

CONTEXT

Metabolic syndrome (MetS) raises the chance of cerebrovascular accidents and cardiovascular illness in type 2 diabetes mellitus (T2DM) individuals. Early identification of MetS allows for suitable prophylactic and treatment strategies to reduce the risks.

AIM

To estimate the prevalence of MetS and its risk factors in T2DM individuals.

SETTINGS AND DESIGN

This cross-sectional study investigated MetS and its component's prevalence among newly diagnosed T2DM at the tertiary care hospital.

METHODS AND MATERIAL

The study was conducted from January 2022 to December 2022 and included 300 participants above 18 years, with most being men (55%, 165), and using the World Health Organization (WHO) STEPS questionnaire for assessing selected risk factors. Along with blood glucose, different components of MetS were assessed, that is serum triglyceride (TG) level, serum high-density lipoprotein (HDL) level, blood pressure (BP) and waist circumference (WC), as per the National Cholesterol Education Program (NCEP) Adult Treatment Panel III (ATP III) criteria.

STATISTICAL ANALYSIS USED

Data analysis includes mean and standard deviation (SD) for numerical variables with an unpaired -test to compare means and percentage and proportions for categorical variables with the Chi-square test for the associations. Multivariate logistic regression was used for assessing the predictors of MetS.

RESULTS

The prevalence of components of MetS, that is obesity, hypertension (HTN), TG and HDL components, was 64.0% (192), 45.7% (137), 46.0% (138) and 30% (90), respectively. Overall, MetS was 57% (170). Moderate activity of 150 min/week, sitting/reclining, WC, diastolic BP, TG and HDL had a significant association with MetS.

CONCLUSIONS

MetS was highly associated with newly diagnosed T2DM with obesity being the most common component.

摘要

背景

代谢综合征(MetS)增加了2型糖尿病(T2DM)患者发生脑血管意外和心血管疾病的几率。早期识别MetS有助于采取适当的预防和治疗策略以降低风险。

目的

评估T2DM患者中MetS及其危险因素的患病率。

设置与设计

这项横断面研究调查了三级护理医院新诊断的T2DM患者中MetS及其组成部分的患病率。

方法与材料

该研究于2022年1月至2022年12月进行,纳入了300名18岁以上的参与者,其中大多数为男性(55%,165名),并使用世界卫生组织(WHO)的逐步调查问卷调查选定的危险因素。根据美国国家胆固醇教育计划(NCEP)成人治疗小组第三次报告(ATP III)标准,除血糖外,还评估了MetS的不同组成部分,即血清甘油三酯(TG)水平、血清高密度脂蛋白(HDL)水平、血压(BP)和腰围(WC)。

所用统计分析

数据分析包括数值变量的均值和标准差(SD),采用不成对t检验比较均值,分类变量采用百分比和比例,采用卡方检验分析关联性。多因素逻辑回归用于评估MetS的预测因素。

结果

MetS各组成部分的患病率,即肥胖、高血压(HTN)、TG和HDL组成部分,分别为64.0%(192名)、45.7%(137名)、46.0%(138名)和30%(90名)。总体而言,MetS患病率为57%(170名)。每周150分钟的中等强度活动、久坐/躺卧、WC、舒张压、TG和HDL与MetS有显著关联。

结论

MetS与新诊断的T2DM高度相关,肥胖是最常见的组成部分。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/892a/11368325/f9bb7cb64168/JFMPC-13-3325-g001.jpg

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