Wahab Ahmed, Muqtadir Jamil, Ansari Abdul R, Tahseen Muhammad, Ayoob Kashif, Zaidi Syed Haris M, Muhammad Arhama S, Khan Aisha, Ahmed Sehar
Internal Medicine, Ziauddin University, Karachi, PAK.
Infectious Diseases, Ziauddin University, Karachi, PAK.
Cureus. 2024 Nov 4;16(11):e72972. doi: 10.7759/cureus.72972. eCollection 2024 Nov.
Introduction Metabolic syndrome (MetS) encompasses a range of diverse conditions, such as hypertension, hyperglycemia, central obesity, dyslipidemia, and diabetes. MetS in non-diabetic elderly patients with acute ischemic stroke can worsen vascular damage and lead to worse outcomes, highlighting the significance of early detection. Objective The objective of this paper was to determine the frequency of MetS in non-diabetic elderly patients with acute ischemic stroke visiting a tertiary care hospital. Material and methods This study was carried out in the medical department of Dr. Ziauddin Hospital in Karachi, Pakistan for a duration of six months from June 20, 2023, to December 19, 2023, following the adoption of the synopsis. All patients meeting the specified criteria and attending Dr. Ziauddin Hospital in Karachi were enrolled in the research. Informed consent was obtained after a thorough description of the methods, possible dangers, and advantages of the study. Each patient underwent the metabolic assessment according to the International Diabetes Federation (IDF) criteria. Data collected was recorded in the provided proforma and electronically utilized for research endeavors. The analysis was conducted utilizing SPSS version 26.0 (IBM Corp., Armonk, NY). Descriptive statistics were computed, and the chi-square/Fisher's exact test was utilized for stratified analysis, with a p-value < 0.05 deemed significant. Result The study included patients aged between 65 and 90 years, with a median age of 74. Among the total population assessed, 133 individuals were male (76.4%) and 41 were female (23.6%). MetS was identified in 116 patients, representing 66.7% of the study population. Conclusion It is to be concluded that MetS was highly prevalent in non-diabetic elderly patients with acute ischemic stroke. This highlights a significant relationship between MetS and the occurrence of cerebrovascular accidents in this demographic. Further exploration and potential interventions targeting MetS in this population could be beneficial for improving health outcomes.
引言
代谢综合征（MetS）涵盖一系列不同的病症，如高血压、高血糖、中心性肥胖、血脂异常和糖尿病。非糖尿病老年急性缺血性脑卒中患者的代谢综合征会加重血管损伤并导致更差的预后，凸显了早期检测的重要性。
目的
本文的目的是确定在一家三级医疗医院就诊的非糖尿病老年急性缺血性脑卒中患者中代谢综合征的发生率。
材料和方法
本研究于2023年6月20日至2023年12月19日在巴基斯坦卡拉奇齐亚丁医院的内科进行，为期六个月，遵循该大纲。所有符合特定标准并在卡拉奇齐亚丁医院就诊的患者均纳入研究。在对研究的方法、可能的风险和益处进行全面描述后，获得了知情同意。每位患者均根据国际糖尿病联盟（IDF）标准进行代谢评估。收集的数据记录在所提供的表格中，并以电子方式用于研究工作。使用SPSS 26.0版（IBM公司，纽约州阿蒙克）进行分析。计算描述性统计数据，并使用卡方检验/费舍尔精确检验进行分层分析，p值<0.05被视为具有统计学意义。
结果
该研究纳入了年龄在65岁至90岁之间的患者，中位年龄为74岁。在评估的总人口中，133人为男性（76.4%），41人为女性（23.6%）。116名患者被诊断为代谢综合征，占研究人群的66.7%。
结论
可以得出结论，代谢综合征在非糖尿病老年急性缺血性脑卒中患者中非常普遍。这凸显了代谢综合征与该人群脑血管意外发生之间的重要关系。针对该人群代谢综合征的进一步探索和潜在干预可能有助于改善健康结局。
