Norkus N S, Kubasik N P, Sine H E
Clin Chem. 1976 May;22(5):683-5.
Three laboratory-prepared urease reagents were compared with a commercial preparation supplied for routine use on the Beckman Blood Urea Nitrogen Analyzer. There were discrepancies in results for urea nitrogen among the four urease reagents when matching serum and the corresponding oxalate/fluoride treated plasma were compared as measured with the Beckman Analyzer and continuous-flow (AutoAnalyzer) method. All four urease preparations were affected by fluoride, but to different extents. We believe that an effective laboratory reagent can be prepared in the laboratory at significantly lower cost.
将三种实验室制备的脲酶试剂与一种用于贝克曼血液尿素氮分析仪常规检测的商业制剂进行了比较。当使用贝克曼分析仪和连续流动（自动分析仪）方法对匹配的血清以及相应的草酸盐/氟化物处理血浆进行检测时，四种脲酶试剂在尿素氮结果上存在差异。所有四种脲酶制剂都受到氟化物的影响，但程度不同。我们认为，可以在实验室以显著更低的成本制备出有效的实验室试剂。
