Luba Mark C, Bangs Scott A, Mohler Andrew M, Stulberg Daniel L
Cigna Healthcare of Arizona, Glendale, Arizona, USA.
Am Fam Physician. 2003 Feb 15;67(4):729-38.
Benign skin tumors are commonly seen by family physicians. The ability to properly diagnose and treat common benign tumors and to distinguish them from malignant lesions is a vital skill for all family physicians. Any lesions for which the diagnosis is uncertain, based on the history and gross examination, should be biopsied for histopathologic examination to rule out malignancy. Lipomas are technically subcutaneous soft tissue tumors, not skin tumors, and controversy exists about whether keratoacanthomas have malignant potential; however, both are discussed in this article because they are common tumors evaluated by family physicians. Diagnosis usually is based on the appearance of the lesion and the patient's clinical history, although biopsy is sometimes required. Treatment includes excision, cryotherapy, curettage with or without electrodesiccation, and pharmacotherapy, and is based on the type of tumor and its location. Generally, excision is the treatment of choice for lipomas, dermatofibromas, keratoacanthomas, pyogenic granulomas, and epidermoid cysts. Cherry angiomas and sebaceous hyperplasia are often treated with laser therapy and electrodesiccation. Common treatments for acrochordons and seborrheic keratoses are cryotherapy and shave excision. Referral is indicated if the family physician is not confident with the diagnostic evaluation or treatment of a lesion, or if a biopsy reveals melanoma.
良性皮肤肿瘤在家庭医生处很常见。正确诊断和治疗常见良性肿瘤并将其与恶性病变区分开来的能力,是所有家庭医生的一项重要技能。对于任何根据病史和大体检查诊断不明确的病变,都应进行活检以进行组织病理学检查,以排除恶性肿瘤。脂肪瘤从技术上讲是皮下软组织肿瘤,而非皮肤肿瘤,关于角化棘皮瘤是否具有恶性潜能也存在争议;然而,本文将对两者进行讨论,因为它们是家庭医生评估的常见肿瘤。诊断通常基于病变的外观和患者的临床病史,不过有时需要进行活检。治疗方法包括切除、冷冻疗法、刮除术(有无电干燥)和药物治疗,具体取决于肿瘤的类型及其位置。一般来说,脂肪瘤、皮肤纤维瘤、角化棘皮瘤、化脓性肉芽肿和表皮样囊肿的首选治疗方法是切除。樱桃状血管瘤和皮脂腺增生通常采用激光治疗和电干燥治疗。皮赘和脂溢性角化病的常见治疗方法是冷冻疗法和剃除术。如果家庭医生对病变的诊断评估或治疗没有信心,或者活检显示为黑色素瘤,则应进行转诊。