de Castro Edilene Alcântara, Soccol Vanete Thomaz, Membrive Norberto, Luz Ennio
Laboratório de Parasitologia Molecular do Departamento de Patologia Básica do Setor de Ciências Biológicas da Universidade Federal do Paraná.
Rev Soc Bras Med Trop. 2002 Sep-Oct;35(5):445-52.
Cases of cutaneous leishmaniasis (CL) in northern Parana State have been reported since the 1950's, but towards the end of the 1980's there has been an increase in the number of human infections. From 1993 to 1998, a study was carried out in an attempt to define the epidemiological profile of leishmaniasis in this region. A total of 316 cases of CL were reported from 35 municipal districts and 16 imported cases. Most cases of CL notified (70.8%) were in the age group of 15 to 49 years old and most of these were males (61.2%). Of the 332 positive patients, 66.8% presented single classic lesions and 31.1% multiple lesions. Most of these lesions were located in the lower limbs (47.7%) while 26.7% were in the arms and 16% on the face. Thirty-two Leishmania stocks were isolated and identified by isoenzymatic characterization using 13 enzymatic systems as Leishmania (Viannia) braziliensis.
自20世纪50年代以来,巴拉那州北部就有皮肤利什曼病(CL)病例的报告,但到20世纪80年代末,人类感染病例数量有所增加。1993年至1998年,开展了一项研究,试图确定该地区利什曼病的流行病学特征。共报告了来自35个市辖区的316例CL病例以及16例输入性病例。报告的大多数CL病例(70.8%)年龄在15至49岁之间,其中大多数为男性(61.2%)。在332例阳性患者中,66.8%表现为单个典型病变,31.1%表现为多个病变。这些病变大多位于下肢(47.7%),而26.7%位于手臂,16%位于面部。通过使用13种酶系统进行同工酶鉴定,分离并鉴定出32株利什曼原虫,为巴西利什曼原虫(维阿尼亚利什曼原虫)。