Rogers R, Denham D A
J Helminthol. 1976 Mar;50(1):21-8. doi: 10.1017/s0022149x00028789.
The effects of levamisole on adults, third stage infective larvae, and microfilariae of Brugia pahangi were studied in in vitro culture and in vivo against developing stages in the vector mosquito and in infected cats. In vitro the drug was effective only at dose levels much higher than can be tolerated by mammals. It was active against the developmental stages of the worm in the vector Aedes aegypti. The drug was strongly microfilaricidal in cats but less effective against adult worms.
研究了左旋咪唑对马来布鲁线虫成虫、第三期感染性幼虫和微丝蚴的作用，包括体外培养以及在体内针对媒介蚊虫体内发育阶段和感染猫体内发育阶段的作用。在体外，该药物仅在远高于哺乳动物耐受剂量的水平下才有效。它对媒介埃及伊蚊体内的虫体发育阶段有活性。该药物在猫体内具有很强的杀微丝蚴作用，但对成虫的效果较差。
