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感染彭亨丝虫并随后用左旋咪唑治疗的猫的血清对彭亨丝虫三期幼虫感染性的影响。

The effect of sera from cats infected with Brugia pahangi and subsequently treated with levamisole on the infectivity of third-stage larvae of B. pahangi.

作者信息

Denham D A, Samad R

机构信息

London School of Hygiene and Tropical Medicine, England.

出版信息

J Parasitol. 1988 Feb;74(1):190-1.

PMID:3357102
Abstract

Cats were treated with levamisole and the infective (L3) stage of Brugia pahangi. Serum from infected cats was subsequently tested for its ability to infect jirds. Jirds autopsied at 33 days postmortem showed significant levels of parasitemia. This is contrary to reports of a previous study wherein serum from humans infected with B. malayi was found to induce cell adherence and death of the L3.

摘要

用左旋咪唑和马来布鲁线虫的感染性(L3)阶段对猫进行治疗。随后检测感染猫的血清感染沙鼠的能力。在死后33天进行尸检的沙鼠显示出显著的寄生虫血症水平。这与之前一项研究的报告相反,在该研究中,发现感染马来布鲁线虫的人类血清会诱导L3细胞粘附和死亡。

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The cat infected with Brugia pahangi as a model of human filariasis.
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