Hoffmann E J, Phelps M E, Mullani N A, Higgins C S, Ter-Pogossian M M
J Nucl Med. 1976 Jun;17(6):493-502.
A whole-body positron-emission transaxial tomograph (PETT III) is described in detail and evaluated in terms of resolution, accuracy, and efficiency. The PETT III utilizes annihilation coincidence detection to provide spatial resolution; high sensitivity is achieved by using 48 Nal(tl) detectors set in a hexagonal array with a multiple-coincidence logic. The assumptions and approximations made in the reconstruction and their effect on image quality are discussed. Phantom studies shows the depth-independent resolution and response of PETT III, as well as its ability to recover activity distribution quantitatively in the cross section measured. Images obtained with patients and normal volunteers show the potential clinical utility of PETT III.
详细描述了一台全身正电子发射断层扫描仪（PETT III），并从分辨率、准确性和效率方面进行了评估。PETT III利用湮灭符合探测来提供空间分辨率；通过使用48个置于六边形阵列中的碘化钠（铊）探测器及多重符合逻辑实现了高灵敏度。讨论了重建过程中所做的假设和近似及其对图像质量的影响。模型研究显示了PETT III与深度无关的分辨率和响应，以及其在测量的横断面上定量恢复活性分布的能力。用患者和正常志愿者获得的图像显示了PETT III潜在的临床应用价值。
