Stevens June, Jones Daniel W, Arnett Donna
Department of Epidemiology, School of Public Health, University of North Carolina Chapel Hill, Chapel Hill, North Carolina, USA.
Obes Res. 2003 Mar;11(3):426-33. doi: 10.1038/oby.2003.58.
To examine associations of aging and birth cohort with body mass index (BMI) in a biethnic cohort.
This was a longitudinal closed cohort study of 14,500 white and African-American men and women, 45 to 64 years of age, followed for 9 years. Aging was defined as the length of the interval in years between baseline and following visits. Birth cohort was defined by the year in which participants were born. Mixed model analyses were used to examine associations of aging, birth cohort, and BMI in four ethnicity-gender groups.
We found that aging was associated with an increase in BMI in white and African-American men and women. The associations between aging and BMI were stronger in the younger birth cohorts. Except for white women, younger birth cohort was associated with a higher BMI. After adjusting for aging, birth cohort was associated with an increase in BMI of 0.1 kg/m(2) [95% confidence interval (95% CI): -0.1, 0.3] among white women. The corresponding values for African-American women, white men, and African-American men are 0.5 kg/m(2) (95% CI: 0.1, 0.9), 0.6 kg/m(2) (95% CI: 0.4, 0.8), and 0.6 kg/m(2) (95% CI: 0.2, 1.0), respectively.
Our analyses show that, in all except white women, people in this age range who were born later have a higher BMI at the same attained age. In all groups, people who are born later gained more weight as they aged. In general, subjects ages 45 to 64 years gained weight as they aged 9 years.
在一个双种族队列中研究衰老和出生队列与体重指数(BMI)之间的关联。
这是一项对14500名45至64岁的白人和非裔美国男性及女性进行的纵向封闭队列研究,随访9年。衰老定义为基线与后续随访之间的时间间隔(以年为单位)。出生队列由参与者的出生年份定义。采用混合模型分析来研究四个种族 - 性别组中衰老、出生队列和BMI之间的关联。
我们发现,在白人和非裔美国男性及女性中,衰老与BMI升高有关。在较年轻的出生队列中,衰老与BMI之间的关联更强。除白人女性外,较年轻的出生队列与较高的BMI相关。在调整衰老因素后,白人女性中出生队列与BMI升高0.1 kg/m²[95%置信区间(95%CI): -0.1,0.3]有关。非裔美国女性、白人男性和非裔美国男性的相应数值分别为0.5 kg/m²(95%CI:0.1,0.9)、0.6 kg/m²(95%CI:0.4,0.8)和0.6 kg/m²(95%CI:0.2,1.0)。
我们的分析表明,除白人女性外,在这个年龄范围内出生较晚的人在相同达到年龄时BMI较高。在所有组中,出生较晚的人随着年龄增长体重增加更多。总体而言,45至6岁的受试者在9年的随访期间体重增加。