Tyers Mike, Mann Matthias
Samuel Lunenfeld Research Institute, Mount Sinai Hospital, and Department of Medical Genetics and Microbiology, University of Toronto, Toronto, Canada M5G 1X5.
Nature. 2003 Mar 13;422(6928):193-7. doi: 10.1038/nature01510.
Proteomics is the study of the function of all expressed proteins. Tremendous progress has been made in the past few years in generating large-scale data sets for protein-protein interactions, organelle composition, protein activity patterns and protein profiles in cancer patients. But further technological improvements, organization of international proteomics projects and open access to results are needed for proteomics to fulfil its potential.
蛋白质组学是对所有表达蛋白质功能的研究。在过去几年中,在生成蛋白质-蛋白质相互作用、细胞器组成、蛋白质活性模式以及癌症患者蛋白质谱的大规模数据集方面取得了巨大进展。但是,蛋白质组学要充分发挥其潜力,还需要进一步的技术改进、国际蛋白质组学项目的组织以及研究结果的开放获取。