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具有固有分散性的球形细胞悬浮液的交流电动行为理论。

Theory of ac electrokinetic behavior of spheroidal cell suspensions with an intrinsic dispersion.

作者信息

Gao Lei, Huang J P, Yu K W

机构信息

Department of Physics, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China.

出版信息

Phys Rev E Stat Nonlin Soft Matter Phys. 2003 Feb;67(2 Pt 1):021910. doi: 10.1103/PhysRevE.67.021910. Epub 2003 Feb 24.

DOI:10.1103/PhysRevE.67.021910
PMID:12636718
Abstract

The dielectric dispersion, dielectrophoretic (DEP), and electrorotational (ER) spectra of spheroidal biological cell suspensions with an intrinsic dispersion in the constituent dielectric constants are investigated. By means of the spectral representation method, we express analytically the characteristic frequencies and dispersion strengths both for the effective dielectric constant and the Clausius-Mossotti factor (CMF). We identify four and six characteristic frequencies for the effective dielectric spectra and CMF, respectively, all of them being dependent on the depolarization factor (or the cell shape). The analytical results allow us to examine the effects of the cell shape, the dispersion strength, and the intrinsic frequency on the dielectric dispersion, DEP, and ER spectra. Furthermore, we include the local-field effects due to the mutual interactions between cells in a dense suspension, and study the dependence of co-field or antifield dispersion peaks on the volume fractions.

摘要

研究了在组成介电常数中具有固有色散的球形生物细胞悬浮液的介电色散、介电泳(DEP)和旋转电场(ER)光谱。通过光谱表示法,我们解析地表达了有效介电常数和克劳修斯 - 莫索蒂因子(CMF)的特征频率和色散强度。我们分别确定了有效介电光谱和CMF的四个和六个特征频率,它们都取决于去极化因子(或细胞形状)。这些解析结果使我们能够研究细胞形状、色散强度和固有频率对介电色散、DEP和ER光谱的影响。此外,我们考虑了由于密集悬浮液中细胞间相互作用引起的局部场效应,并研究了同场或反场色散峰对体积分数的依赖性。

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引用本文的文献

1
The dielectric behavior of nonspherical biological cell suspensions: an analytic approach.非球形生物细胞悬浮液的介电特性:一种分析方法。
Biophys J. 2010 Jul 7;99(1):163-74. doi: 10.1016/j.bpj.2010.04.006.
2
Dielectric behaviour of graded spherical cells with an intrinsic dispersion.具有本征色散的梯度球形细胞的介电行为
Eur Phys J E Soft Matter. 2004 May;14(1):97-104. doi: 10.1140/epje/i2003-10142-3.