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短疗程抗生素治疗是否能更好地满足患者期望?

Does short-course antibiotic therapy better meet patient expectations?

作者信息

Perez-Gorricho B, Ripoll M

机构信息

Division of Infectious Diseases, Children's Hospital Niño Jesus, Universidad Autónoma de Madrid, Menéndez Pelayo 65, 28009 Madrid, Spain.

出版信息

Int J Antimicrob Agents. 2003 Mar;21(3):222-8. doi: 10.1016/s0924-8579(02)00360-6.

Abstract

A pan-European market research study of 3254 patients designed to determine patient attitudes, expectations and behaviour to antibiotic management of mild-moderate RTIs, identified three key drivers of perceived antibiotic efficacy: length of antibiotic course, time to onset of symptom relief and time to complete resolution of symptoms. Azithromycin was selected as "drug therapy of shortest dosage schedule" for common outpatient infections. The results demonstrate that once-daily, short-course treatment is perceived to be significantly more effective than longer antibiotic courses and thus, better meets patient expectations of therapy. This perception of efficacy with short-course therapy also correlates with overall satisfaction with management by the physician and compliance with therapy. These findings have important implications for the way physicians manage patients with mild-moderate RTIs.

摘要

一项针对3254名患者的泛欧洲市场研究旨在确定患者对轻中度呼吸道感染抗生素治疗的态度、期望和行为,该研究确定了影响抗生素疗效认知的三个关键驱动因素:抗生素疗程时长、症状缓解开始时间和症状完全消退时间。阿奇霉素被选为常见门诊感染的“最短给药方案药物治疗”。结果表明,每日一次的短疗程治疗被认为明显比更长疗程的抗生素治疗更有效,因此,能更好地满足患者对治疗的期望。这种对短疗程治疗疗效的认知也与患者对医生治疗管理的总体满意度以及治疗依从性相关。这些发现对医生治疗轻中度呼吸道感染患者的方式具有重要意义。

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