Davies Justine Ina, Struthers Allan D
Department of Clinical Pharmacology, Ninewells Hospital and Medical School, Dundee DD1 9SY, Scotland, UK.
J Hypertens. 2003 Mar;21(3):463-72. doi: 10.1097/00004872-200303000-00004.
The study of the pulse using the technique of applanation tonometry is undergoing a resurgence with the development of new computerized equipment. We aim here to present a critical review of the uses, potential uses, strengths and weaknesses of the technique of applanation tonometry for the assessment of augmentation index and pulse wave velocity. We will review the technique of applanation tonometry, the physiological factors affecting pulse wave velocity and pulse wave analysis, the changes in pulse wave velocity and pulse wave analysis with pharmacological interventions, and the use of the technique of applanation tonometry as a prognostic tool. We conclude that, although the technique of applanation tonometry initially seems promising, several pertinent issues need to be addressed before it can be used reliably as a clinical or research tool. Importantly, use of the technique of applanation tonometry to derive the central waveform from non-invasively acquired peripheral data needs to be validated prospectively.
随着新型计算机设备的发展，采用压平眼压测量技术对脉搏的研究正在复兴。我们旨在对压平眼压测量技术在评估增强指数和脉搏波速度方面的用途、潜在用途、优点和缺点进行批判性综述。我们将回顾压平眼压测量技术、影响脉搏波速度和脉搏波分析的生理因素、药物干预时脉搏波速度和脉搏波分析的变化，以及压平眼压测量技术作为一种预后工具的应用。我们得出结论，尽管压平眼压测量技术最初看起来很有前景，但在它能够可靠地用作临床或研究工具之前，有几个相关问题需要解决。重要的是，使用压平眼压测量技术从非侵入性获取的外周数据中得出中心波形需要进行前瞻性验证。
