Qu Guangzhi, Kaur Judith S, Seward James B
Divisions of Medical Oncology, Mayo Clinic Rochester, MN 55905, USA.
Am J Med Sci. 2003 Mar;325(3):157-9. doi: 10.1097/00000441-200303000-00009.
We present a rare case of malignant melanoma of unknown primary origin presenting as cardiac and cholecystic masses. In this 72-year-old man, a cardiac lesion caused right ventricular outlet obstruction, and gallbladder lesions led to hemobilia. Right atrial and gallbladder metastases were resected. After 2 years of disease-free survival, the patient had recurrent skin lesions, which were treated with local resection and dacarbazine. The patient has survived for more than 5 years after initial diagnosis, with continued complete clinical remission. This case illustrates the importance of aggressive surgical resection and chemotherapy in the treatment of metastatic malignant melanoma.
我们报告一例罕见的原发性不明的恶性黑色素瘤，表现为心脏和胆囊肿块。在这名72岁男性患者中，心脏病变导致右心室流出道梗阻，胆囊病变导致胆道出血。切除了右心房和胆囊转移灶。经过2年无病生存期后，患者出现复发性皮肤病变，接受了局部切除和达卡巴嗪治疗。患者自初次诊断后已存活超过5年，临床持续完全缓解。该病例说明了积极的手术切除和化疗在转移性恶性黑色素瘤治疗中的重要性。
