Chang Andrew C, Yee John, Orringer Mark B, Iannettoni Mark D
Section of Thoracic Surgery, University of Michigan Medical Center, Ann Arbor, Michigan 48109-0344, USA.
Ann Thorac Surg. 2002 Dec;74(6):1942-6; discussion 1946-7. doi: 10.1016/s0003-4975(02)04164-4.
Tissue diagnosis of either interstitial lung disease or indeterminate pulmonary nodules can be obtained by either limited thoracotomy or thoracoscopic lung biopsy. Both procedures traditionally have required hospital admission. We report a series of patients undergoing outpatient thoracoscopic lung biopsy to demonstrate the safety and efficacy of this practice.
Sixty-two ambulatory patients with a clinical diagnosis of either interstitial lung disease or indeterminate pulmonary nodule(s) underwent thoracoscopic lung biopsy between June 2000 and June 2001. All procedures were performed with double-lumen endotracheal anesthesia and stapled wedge resection. Chest tubes were removed if no air leak was present and if chest radiograph demonstrated no residual pneumothorax.
Of 62 patients undergoing thoracoscopic lung biopsy, 45 (72.5%) were discharged home within 8 hours of observation on the day of operation. Fourteen (22.5%) were discharged within 23 hours of their operation. Reasons for 23-hour observation included significant comorbidity (8), pain management (4), postoperative air leak (1), and conversion to muscle-sparing thoracotomy (1). Three (5%) required admission for prolonged air leak (2) or conversion to muscle-sparing thoracotomy (1). Diagnoses were obtained in 61 patients, including neoplasm (25), interstitial lung disease (18), granulomatous disease (7), and other (11). One patient was readmitted for pneumothorax. Patients diagnosed with nonbronchogenic pulmonary metastases were more likely to be discharged on the day of operation. No differences in age, smoking status, or preoperative pulmonary function testing were observed between patients requiring short-stay observation and those discharged immediately after operation.
Outpatient thoracoscopic lung biopsy is safe and effective, and has become our procedure of choice for diagnosis of either interstitial or focal lung disease.
间质性肺疾病或不明肺结节的组织诊断可通过有限开胸手术或胸腔镜肺活检获得。传统上,这两种手术都需要住院。我们报告了一系列接受门诊胸腔镜肺活检的患者,以证明这种做法的安全性和有效性。
2000年6月至2001年6月期间,62例临床诊断为间质性肺疾病或不明肺结节的门诊患者接受了胸腔镜肺活检。所有手术均采用双腔气管内麻醉和吻合器楔形切除术。如果没有漏气且胸部X线片显示无残留气胸,则拔除胸管。
62例接受胸腔镜肺活检的患者中,45例(72.5%)在手术当天观察8小时内出院回家。14例(22.5%)在手术后23小时内出院。23小时观察的原因包括严重合并症(8例)、疼痛管理(4例)、术后漏气(1例)和转为保留肌肉的开胸手术(1例)。3例(5%)因持续漏气(2例)或转为保留肌肉的开胸手术(1例)需要住院。61例患者获得了诊断,包括肿瘤(25例)、间质性肺疾病(18例)、肉芽肿性疾病(7例)和其他(11例)。1例患者因气胸再次入院。诊断为非支气管源性肺转移的患者更有可能在手术当天出院。需要短期观察的患者与手术后立即出院的患者在年龄、吸烟状况或术前肺功能测试方面没有差异。
门诊胸腔镜肺活检安全有效,已成为我们诊断间质性或局灶性肺疾病的首选方法。