Kurz Haymo, Burri Peter H, Djonov Valentin G
Institute of Anatomy II, University of Freiburg, D-79104 Freiburg, Germany.
News Physiol Sci. 2003 Apr;18:65-70. doi: 10.1152/nips.01417.2002.
During most instances of angiogenesis, not only are the capillaries or terminal vessels generated and modified, but the supplying vascular system is subjected to remodeling as well. Intussusception, i.e., transluminal pillar formation, is one essential mechanism for growth, arborization, bifurcation remodeling, and pruning. Complex and efficient vascular beds can thus be generated by local interactions between vascular cells and hemodynamic conditions.
在大多数血管生成的情况下，不仅毛细血管或终末血管会生成并发生改变，供应血管系统也会经历重塑。套叠，即腔内柱形成，是生长、分支、分叉重塑和修剪的一种重要机制。因此，通过血管细胞与血流动力学条件之间的局部相互作用，可以生成复杂而高效的血管床。
