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临床药理学家在动物健康方面的作用。

The role of the clinical pharmacologist in animal health.

作者信息

Langston Cory, Clarke Cyril R

机构信息

College of Veterinary Medicine, Box 6100, Mississippi State, MS 39762-6100, USA.

出版信息

AAPS PharmSci. 2002;4(4):E36. doi: 10.1208/ps040436.

Abstract

Like most scientific disciplines, pharmacology is replete with subspecialties. Certainly most scientists recognize the value of animal studies in drug development for human pharmaceuticals. However, animals as the target species also represent a major focus of investigation. According to recent estimates, in the United States for the year 2000, 98.1 million cattle, 59.8 million pigs, and 1.5 billion chickens existed. Added to that estimate were companion animals, including 4 million horses, 59 million cats, and 52.9 million dogs. The estimate does not include the so-called "minor" species, such as 7 million sheep and 320,000 acres of freshwater fish production. In most respects, the medical needs of these animals are addressed in a manner parallel to that of human medicine. One such parallel, with certain distinct differences from its human counterpart, is veterinary clinical pharmacology.

摘要

与大多数科学学科一样,药理学也有许多子专业。当然,大多数科学家都认识到动物研究在人类药物研发中的价值。然而,作为目标物种的动物也是研究的一个主要焦点。根据最近的估计,2000年美国有9810万头牛、5980万头猪和15亿只鸡。这个估计还包括伴侣动物,其中有400万匹马、5900万只猫和5290万只狗。该估计不包括所谓的“小众”物种,比如700万只羊和32万英亩的淡水鱼养殖。在大多数方面,这些动物的医疗需求与人类医学的处理方式类似。兽医临床药理学就是其中一种类似情况,不过与人类临床药理学有某些明显差异。

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