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[儿童泌尿系统感染中的血清抗体。其意义及与肾盂肾炎的关系]

[Serum antibodies in urinary infection in children. Significance and relation to pyelonephritis].

作者信息

Bégué P, Lasfargues G, Befekadu E, Quiniou F, Laplane R

出版信息

Nouv Presse Med. 1976 Feb 7;5(6):339-42.

PMID:1264703
Abstract

Serum antibodies were measured repeatedly in 176 cases of urinary tract infections in children. The method used, passive haemagglutination with the bacterial antigen of the patient's urinary infection, gives a positive reading from 1/160. Antibodies were found in 139 cases and the lower limit compatible with a diagnosis of pyelonephritis was 1/2560. The result may, however, be negative in infants of less than one year. As in the first publication, the authors describe three types of curves of progression. Analysis confirms the relationship between persistent antibodies and evolutive pyelonephritis. Experimental results and a comparison of clinical and pathological findings are discussed and support the notion of the value of a persistent high antibody level in the diagnosis of chronic pyelonephritis.

摘要

对176例儿童尿路感染病例反复检测血清抗体。所采用的方法是用患者尿路细菌感染的细菌抗原进行被动血凝试验,阳性读数从1/160开始。在139例中发现了抗体,与肾盂肾炎诊断相符的下限为1/2560。然而,一岁以下婴儿的检测结果可能为阴性。如同首次发表的文章一样,作者描述了三种进展曲线类型。分析证实了持续抗体与进展性肾盂肾炎之间的关系。讨论了实验结果以及临床和病理结果的比较,支持了持续高抗体水平在慢性肾盂肾炎诊断中有价值这一观点。

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