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[通过对菌尿的免疫荧光研究和体液抗体测量对儿童尿路感染进行定位]

[Localization of urinary tract infection in children by immunofluorescent study of bacteriuria and measurement of humoral antibodies].

作者信息

Bensman A, Desnottes J F, Quiniou-Mandar F, Befekadu E, Bégué P

出版信息

Arch Fr Pediatr. 1978 Mar;35(3):242-52.

PMID:352302
Abstract

In 62 children presenting with a urinary infection, the immuno-fluorescent (I.F.) study of immunoglobulins fixed on the cell wall of urinary bacteria was performed jointly with the titration of serum antibodies towards the same bacteria. This study revealed that: 1. There was a correlation between I.F. and serodiagnosis in 82% of the cases. 2. There was a correlation between the localization of the urinary tract infection, as assessed by the classical biochemical means, and the results of I.F. and antibody measurements. Positivity of either I.F. or serodiagnosis, or of both tests, is significantly related with upper urinary tract infection wheras the negativity of the two tests is observed, at the exception of children under 1 year of age, in lower urinary tract infection. 3. There was a correlation between the site of infection and the results of I.F. and antibody measurements. In upper urinary tract infections, either I.F. or serological tests, or both are positive, whereas in lower urinary tract infections both tests are negative, except in children under the age of 1 year.

摘要

在62例患有泌尿系统感染的儿童中,对固定在泌尿系统细菌细胞壁上的免疫球蛋白进行了免疫荧光(I.F.)研究,并同时对针对相同细菌的血清抗体进行了滴定。该研究表明:1. 在82%的病例中,免疫荧光与血清学诊断之间存在相关性。2. 通过经典生化方法评估的泌尿系统感染部位与免疫荧光及抗体测量结果之间存在相关性。免疫荧光或血清学诊断阳性,或两者均阳性,与上泌尿系统感染显著相关,而除1岁以下儿童外,在下泌尿系统感染中观察到两项检测均为阴性。3. 感染部位与免疫荧光及抗体测量结果之间存在相关性。在上泌尿系统感染中,免疫荧光或血清学检测,或两者均为阳性,而在下泌尿系统感染中,除1岁以下儿童外,两项检测均为阴性。

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