Sep-Kowalikowa Barbara
I Klinika Chorób Psychicznych AM w Gdańsku.
Psychiatr Pol. 2002 Nov-Dec;36(6 Suppl):99-108.
Effects of treatment of depression with combined antidepressants and phototherapy and antidepressants alone were compared. Phototherapy was applied 5 days a week, up to 1.5 hour a day, 4500 Lux approximately. Mental status was evaluated by the use of HAMD and BDI in the beginning and after two weeks of treatment. Final results were similar in both groups but in the group treated with combined therapy significant improvement just after the first week of treatment was seen. It can be suggested that phototherapy when applied together with antidepressants may accelerate remission. Particularly good response was seen in patients with bipolar affective disorder. Influence of two kinds of treatment on particular symptoms of depression was different. In patients who were given only antidepressants improvement of sleep and appetite was observed first. Patients treated also with phototherapy reported increase of energy and mood improvement.
比较了联合使用抗抑郁药和光疗与单独使用抗抑郁药治疗抑郁症的效果。光疗每周进行5天，每天最多1.5小时，光照强度约为4500勒克斯。在治疗开始时和治疗两周后，使用汉密尔顿抑郁量表（HAMD）和贝克抑郁量表（BDI）评估精神状态。两组的最终结果相似，但在联合治疗组中，治疗第一周后就出现了显著改善。可以认为，光疗与抗抑郁药联合使用可能会加速缓解。双相情感障碍患者的反应尤其良好。两种治疗方法对抑郁症特定症状的影响有所不同。仅服用抗抑郁药的患者首先观察到睡眠和食欲有所改善。同时接受光疗的患者报告精力增加且情绪改善。
