• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

抗抑郁药无反应者的强光增强作用。

Bright light augmentation in antidepressant nonresponders.

作者信息

Levitt A J, Joffe R T, Kennedy S H

机构信息

Mood Disorders Clinic, Toronto General Hospital, Ontario, Canada.

出版信息

J Clin Psychiatry. 1991 Aug;52(8):336-7.

PMID:1869495
Abstract

BACKGROUND

This study was designed to examine the potential benefit of the addition of bright lights to antidepressant treatment in depressed subjects.

METHOD

Ten patients who presented during the winter months with major depression and who had failed an adequate trial of antidepressants or who had relapsed following a successful course of antidepressants underwent a 2-week course of bright light therapy.

RESULTS

Augmentation with bright lights resulted in substantial improvement in 7 of the 10 patients.

CONCLUSION

Bright light augmentation may provide a useful treatment alternative for patients with treatment-resistant depression.

摘要

背景

本研究旨在探讨在抑郁症患者的抗抑郁治疗中添加强光的潜在益处。

方法

10名在冬季出现重度抑郁症的患者,他们在充分试用抗抑郁药后治疗失败,或在成功接受抗抑郁药治疗后复发,接受了为期2周的强光治疗。

结果

10名患者中有7名通过添加强光治疗取得了显著改善。

结论

对于难治性抑郁症患者,强光增效治疗可能是一种有效的治疗选择。

相似文献

1
Bright light augmentation in antidepressant nonresponders.抗抑郁药无反应者的强光增强作用。
J Clin Psychiatry. 1991 Aug;52(8):336-7.
2
Adjunctive bright light in non-seasonal major depression.非季节性重度抑郁症中的辅助性强光疗法
Acta Psychiatr Scand Suppl. 2004(425):7-28. doi: 10.1111/j.1600-0447.2004.00460_2.x.
3
Adjunctive bright light in non-seasonal major depression: results from clinician-rated depression scales.非季节性重度抑郁症中的辅助性强光疗法:临床医生评定的抑郁量表结果
Acta Psychiatr Scand. 2005 Aug;112(2):117-25. doi: 10.1111/j.1600-0447.2005.00574.x.
4
[Phototherapy as a supporting treatment in depressive patients].[光疗作为抑郁症患者的辅助治疗方法]
Psychiatr Pol. 2002 Nov-Dec;36(6 Suppl):99-108.
5
Bright light therapy stabilizes the antidepressant effect of partial sleep deprivation.强光疗法可稳定部分睡眠剥夺的抗抑郁效果。
Biol Psychiatry. 1996 Jan 1;39(1):16-21. doi: 10.1016/0006-3223(95)00086-0.
6
Switching versus augmentation: a prospective, naturalistic comparison in depressed, treatment-resistant patients.换药与增效:对难治性抑郁症患者的一项前瞻性、自然主义比较研究
J Clin Psychiatry. 2001 Feb;62(2):135-42; quiz 143.
7
Possible augmentation of antidepressant response by buspirone.丁螺环酮可能增强抗抑郁反应。
J Clin Psychiatry. 1991 May;52(5):217-20.
8
A pilot sequential study of cognitive therapy and pharmacotherapy of atypical depression.非典型抑郁症认知疗法与药物疗法的一项先导性序贯研究。
J Clin Psychiatry. 1992 May;53(5):166-70.
9
[Sleep deprivation as a predictor of response to light therapy in major depression].[睡眠剥夺作为重度抑郁症患者对光疗法反应的预测指标]
Fortschr Neurol Psychiatr. 2001 Apr;69(4):156-63. doi: 10.1055/s-2001-12678.
10
The lack of sustained effect of bright light, after discontinuation, in non-seasonal major depression.在非季节性重度抑郁症中,强光疗法在停止治疗后缺乏持续效果。
Psychol Med. 2006 Sep;36(9):1247-52. doi: 10.1017/S0033291706008105. Epub 2006 Jun 7.

引用本文的文献

1
Increased Interleukin-6 Levels in Responders with Treatment-Resistant Depression After Bright Light Therapy.明亮光疗法后难治性抑郁症应答者体内白细胞介素-6水平升高。
Biomolecules. 2025 Feb 16;15(2):295. doi: 10.3390/biom15020295.
2
Plasma Brain-Derived Neurotrophic Factor Levels in First-Episode and Recurrent Major Depression and before and after Bright Light Therapy in Treatment-Resistant Depression.首发和复发性重度抑郁症及治疗抵抗性抑郁症患者经强光治疗前后的血浆脑源性神经营养因子水平。
Biomolecules. 2023 Sep 20;13(9):1425. doi: 10.3390/biom13091425.
3
Augmentation of light therapy in difficult-to-treat depressed patients: an open-label trial in both unipolar and bipolar patients.
难治性抑郁症患者光疗法的强化:一项针对单相和双相患者的开放标签试验。
Neuropsychiatr Dis Treat. 2015 Sep 9;11:2331-8. doi: 10.2147/NDT.S74861. eCollection 2015.
4
Light treatment of mood disorders.情绪障碍的光照治疗
Dialogues Clin Neurosci. 2003 Dec;5(4):353-65. doi: 10.31887/DCNS.2003.5.4/bparry.
5
A primary care focus on the treatment of patients with major depressive disorder.以治疗主要抑郁障碍患者为重点的初级保健。
Am J Med Sci. 2011 Oct;342(4):324-30. doi: 10.1097/MAJ.0b013e318210ff56.
6
Side effects of adjunct light therapy in patients with major depression.
Eur Arch Psychiatry Clin Neurosci. 1997;247(5):252-8. doi: 10.1007/BF02900303.
7
Light, melatonin and the sleep-wake cycle.光线、褪黑素与睡眠-清醒周期。
J Psychiatry Neurosci. 1994 Nov;19(5):345-53.
8
The effect of adjunctive light therapy on ameliorating breakthrough depressive symptoms in adolescent-onset bipolar disorder.辅助光疗法对改善青少年期双相情感障碍中突破性抑郁症状的作用。
J Psychiatry Neurosci. 1995 May;20(3):226-32.