Vera-Gil A, Pérez-Castejón M C, Lahoz M, Aisa J, Recreo M P, Serrano P, Pes N
Department of Human Anatomy and Histology, Faculty of Medicine, University of Zaragoza, Zaragoza, Spain.
Histol Histopathol. 2003 Apr;18(2):467-73. doi: 10.14670/HH-18.467.
We have studied the autoradiographic uptake of 65Zn in the cerebellum and brainstem of the rat, contrasting these results with Timm's positivity in these structures. Both, autoradiographic uptake and histochemical positivity, have demonstrated Zinc in a location that could be accepted as in climbing fibres and glomeruli of the cerebellum cortex, and also in brainstem neurons that project their axons to the cerebellum cortex, suggesting a circuit where zinc may act as a neuromodulator.
我们研究了65锌在大鼠小脑和脑干中的放射自显影摄取情况,并将这些结果与这些结构中Timm染色阳性情况进行对比。放射自显影摄取和组织化学阳性结果均显示,锌存在于小脑皮质的攀缘纤维和小球以及向小脑皮质投射轴突的脑干神经元中,这表明存在一个锌可能作为神经调节剂发挥作用的回路。