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Synthesis of 2,4-disubstituted 5-aminopyrimidine-6-carboxylic acids derivatives part I.

作者信息

Machoń Z, Jasztold-Howorko R

出版信息

Pol J Pharmacol Pharm. 1976 Jan-Feb;28(1):61-7.

PMID:1264859
Abstract

5-Benzoyloaminoorotic acid in a reaction with POCl3 forms 2,4-dichloro-5-benzylo-aminopyrimidine-6-carboxylic acid lactam 3, which heated with aliphatic and aromatic amines gives corresponding amides 6-11. These compounds don't show any antiinflammatory or antivirus activity.

摘要

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