小鼠中两种肌营养不良表达形式的等位基因dy和dy2J的比较。

Comparison of dy and dy2J, two alleles expressing forms of muscular dystrophy in the mouse.

作者信息

Macpike A D, Meier H

出版信息

Proc Soc Exp Biol Med. 1976 Apr;151(4):670-2. doi: 10.3181/00379727-151-39283.

Abstract

The muscular dystrophies caused by dy and dy2J on a C57BL/6J genetic background are similar in quality. At 1 month, slight differences occur in distribution of the muscle lesions, diffuse and focal, respectively, but at 3 months little, if any, differences exist. The dy dystrophy appears the same histologically on either the C57BL/6J or original 129/ReJ and 129B6F backgrounds.

摘要

在C57BL/6J遗传背景下，由dy和dy2J引起的肌营养不良在性质上相似。在1个月时，肌肉损伤的分布出现轻微差异，分别为弥漫性和局灶性，但在3个月时，即使有差异也很小。在C57BL/6J、原始的129/ReJ和129B6F背景下，dy肌营养不良在组织学上表现相同。