Nigro Luciano, Larocca Licia, Massarelli Laura, Patamia Ildebrando, Minniti Salvatore, Palermo Filippo, Cacopardo Bruno
Infectious Diseases Unit, University of Catania, c/o Ascoli-Tomaselli Hospital, via Passo Gravina 185, 95125 Catania, Italy.
J Travel Med. 2003 Mar-Apr;10(2):128-30. doi: 10.2310/7060.2003.31714.
Blastocystis hominis, previously considered a harmless yeast, is now classified as a protozoan inhabiting the human intestinal tract. The pathogenicity of B. hominis remains controversial and is currently the subject of extensive debate.1- 5 As a result of the uncertainty surrounding the pathogenic role of B. hominis, large-scale treatment trials of B. hominis infection have so far been lacking. In spite of this, several drugs have been reported to be active against the parasite.6-8 The present study was carried out in order to evaluate the efficacy of metronidazole treatment in inducing clinical remission and parasitologic eradication in immunocompetent individuals with B. hominis as the only evident cause of diarrhea.
人芽囊原虫，以前被认为是一种无害的酵母，现在被归类为栖息于人类肠道的原生动物。人芽囊原虫的致病性仍存在争议，目前是广泛辩论的主题。1 - 5由于围绕人芽囊原虫致病作用的不确定性，迄今为止缺乏针对人芽囊原虫感染的大规模治疗试验。尽管如此，已有几种药物据报道对该寄生虫有活性。6 - 8本研究旨在评估甲硝唑治疗对免疫功能正常、以人芽囊原虫作为腹泻唯一明显病因的个体诱导临床缓解和寄生虫学清除的疗效。
