小鼠肝脏中Δ1-四氢大麻酚的三种单羟基酸和两种二羟基酸代谢物的表征
Characterization of three monohydroxyacid and two dihydroxyacid metabolites of delta 1-tetrahydrocannabinol in mouse liver.
作者信息
Harvey D J, Paton W D
出版信息
Res Commun Chem Pathol Pharmacol. 1976 Apr;13(4):585-99.
PMID:1265340
Abstract
Delta 1-Tetrahydrocannabinol-7-oic acid, together with its 2 inches-, 3 inches- and 6 alpha-monohydroxy and 2 inches, 6 alpha- and 3 inches, 6 alpha-dihydroxy derivatives have been characterized by combined gas chromatography and mass spectrometry in organic extracts of mouse liver following large doses of delta 1-tetrahydrocannabinol.
摘要
在给小鼠大剂量注射δ1-四氢大麻酚后，通过气相色谱和质谱联用技术对其肝脏有机提取物中的δ1-四氢大麻酚-7-酸及其2英寸、3英寸和6α-单羟基衍生物以及2英寸，6α-和3英寸，6α-二羟基衍生物进行了表征。
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