Whitehead C C, Blair R, Bannister D W, Evans A J, Jones R M
Res Vet Sci. 1976 Mar;20(2):180-4.
Three experiments were carried out to investigate the involvement of vitamins in the fatty liver and kidney syndrome. The compounds studied, singly and in combination, were thiamin, riboflavin, nicotinic acid, pyridoxine, pantothenic acid, biotin, folic acid vitamin B12, ascorbic acid, choline and inositol and of these, only biotin prevented the syndrome. The minimum levels of supplemental dietary biotin required to prevent mortality varied from 0-05 to 0-15 mg/kg, depending on the diet. These levels were higher than the amounts required for maximum liveweight.
进行了三项实验以研究维生素与脂肪肝和肾病综合征的关系。单独及组合研究的化合物有硫胺素、核黄素、烟酸、吡哆醇、泛酸、生物素、叶酸、维生素B12、抗坏血酸、胆碱和肌醇，其中只有生物素可预防该综合征。预防死亡所需补充膳食生物素的最低水平因饮食而异，为0.05至0.15毫克/千克。这些水平高于最大体重所需的量。
