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核心技术专利：CN118964589B侵权必究

核心技术专利：CN118964589B侵权必究

Br Poult Sci. 1977 Nov;18(6):749-53. doi: 10.1080/00071667708416430.

Birds affected by fatty liver and kidney syndrome (FLKS) had elevated concentrations of serum Na+, K+, lactate, pyruvate and uric acid and reduced concentrations of serum HCO-3 and glucose. 2. Short-term treatment with biotin or animal tallow reduced the mortality from FLKS and prevented the clinical signs. 3. Lactic acidosis may be a major factor contributing to the mortality and physical symptoms observed in birds affected by FLKS. The lactic acidosis and the hypoglycaemia observed in FLKS are due primarily to an accumulation of pyruvate as a result of an insufficiency of biotin for normal pyruvate carboxylase activity.

受脂肪肝和肾病综合征（FLKS）影响的鸟类血清中Na+、K+、乳酸、丙酮酸和尿酸浓度升高，血清HCO-3和葡萄糖浓度降低。2. 用生物素或动物脂肪进行短期治疗可降低FLKS的死亡率并预防临床症状。3. 乳酸酸中毒可能是导致受FLKS影响的鸟类出现死亡和身体症状的主要因素。FLKS中观察到的乳酸酸中毒和低血糖主要是由于生物素不足导致丙酮酸羧化酶正常活性不足，从而使丙酮酸积累所致。

Br Poult Sci. 1977 Nov;18(6):749-53. doi: 10.1080/00071667708416430.

Birds affected by fatty liver and kidney syndrome (FLKS) had elevated concentrations of serum Na+, K+, lactate, pyruvate and uric acid and reduced concentrations of serum HCO-3 and glucose. 2. Short-term treatment with biotin or animal tallow reduced the mortality from FLKS and prevented the clinical signs. 3. Lactic acidosis may be a major factor contributing to the mortality and physical symptoms observed in birds affected by FLKS. The lactic acidosis and the hypoglycaemia observed in FLKS are due primarily to an accumulation of pyruvate as a result of an insufficiency of biotin for normal pyruvate carboxylase activity.

受脂肪肝和肾病综合征（FLKS）影响的鸟类血清中Na+、K+、乳酸、丙酮酸和尿酸浓度升高，血清HCO-3和葡萄糖浓度降低。2. 用生物素或动物脂肪进行短期治疗可降低FLKS的死亡率并预防临床症状。3. 乳酸酸中毒可能是导致受FLKS影响的鸟类出现死亡和身体症状的主要因素。FLKS中观察到的乳酸酸中毒和低血糖主要是由于生物素不足导致丙酮酸羧化酶正常活性不足，从而使丙酮酸积累所致。