Rüttner J R
Schweiz Med Wochenschr. 1976 Apr 3;106(14):465-7.
The value of open lung biopsies for the diagnosis of diffuse interstitial lung fibrosis is discussed. Except for few cases, e.g. granulomatous processes, needle biopsies are not a reliable method. In diffuse lung fibroses of unknown etiology which are not related to systemic diseases such as collagen diseases, combined electronmicroscopy and EDAX (Energy Dispersive X-ray Analysis) may reveal pneumoconiotic lesions due to unperceived mineral-dust exposure.
本文讨论了开放性肺活检对弥漫性间质性肺纤维化的诊断价值。除少数情况（如肉芽肿性病变）外，针吸活检并非可靠的诊断方法。对于病因不明且与胶原病等全身性疾病无关的弥漫性肺纤维化，联合电子显微镜检查和能谱分析（能量色散X射线分析）可能会发现因未察觉的矿物粉尘暴露所致的尘肺病变。
