脑膜炎奈瑟菌RTX蛋白对幼鼠的毒力并非必需。
Neisseria meningitidis RTX proteins are not required for virulence in infant rats.
作者信息
Forman Stanislav, Linhartova Irena, Osicka Radim, Nassif Xavier, Sebo Peter, Pelicic Vladimir
机构信息
Laboratory of Molecular Biology of Bacterial Pathogens, Institute of Microbiology, Czech Academy of Sciences, CZ-142 20 Prague 4, Czech Republic.
出版信息
Infect Immun. 2003 Apr;71(4):2253-7. doi: 10.1128/IAI.71.4.2253-2257.2003.
Abstract
RTX cytotoxins play an important role in virulence of numerous gram-negative pathogens. Unexpectedly, however, we show here that the RTX proteins of Neisseria meningitidis are dispensable for virulence in the infant rat model of infection.
摘要
RTX细胞毒素在众多革兰氏阴性病原体的毒力中发挥着重要作用。然而，出乎意料的是，我们在此表明，脑膜炎奈瑟菌的RTX蛋白在幼鼠感染模型的毒力中并非必需。
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