McNamara Patrick, Durso Raymon
Department of Neurology, Boston University School of Medicine, MA, USA.
Brain Lang. 2003 Mar;84(3):414-23. doi: 10.1016/s0093-934x(02)00558-8.
Pragmatic communication abilities may depend on intact frontal lobe systems. Independent evidence suggests that some persons with Parkinson's disease (PD) are impaired on measures of frontal lobe function.
We therefore hypothesized in Study 1 that pragmatic communication skills would be impaired in some persons with PD and would be linked to frontal dysfunction in these patients. In Study 2 we hypothesized that PD patients would be unaware of their pragmatic communication deficits.
In Study 1 we administered tests of pragmatic abilities and frontal lobe functioning to twenty-two persons with Parkinson's disease (PD) and 10 healthy controls. In Study 2 we obtained self-ratings of pragmatic abilities from 11 PD patients and then checked these self-ratings against ratings of these same abilities by the patient's spouses.
We found in Study 1 that patients with PD were: (a) significantly impaired on measures of pragmatic communication abilities, especially in the areas of conversational appropriateness, turn-taking, prosodics and proxemics, and that this impairment was significantly related to measures of frontal lobe function. In study 2 we found that PD patients overestimated their own abilities relative to spousal ratings of those abilities and thus were unaware of the extent of their problems with pragmatic social communication skills.
We conclude that pragmatic social communication skills are impaired in PD and that this impairment may be related to frontal lobe dysfunction.
语用交流能力可能依赖于完整的额叶系统。独立证据表明，一些帕金森病（PD）患者在额叶功能测量方面存在缺陷。
因此，我们在研究1中假设，一些PD患者的语用交流技能会受损，且这种受损与这些患者的额叶功能障碍有关。在研究2中，我们假设PD患者不会意识到自己的语用交流缺陷。
在研究1中，我们对22名帕金森病患者和10名健康对照者进行了语用能力和额叶功能测试。在研究2中，我们从11名PD患者那里获得了语用能力的自我评估，然后将这些自我评估与患者配偶对相同能力的评估进行对照。
我们在研究1中发现，PD患者：（a）在语用交流能力测量方面存在显著缺陷，尤其是在对话恰当性、轮流发言、韵律和空间关系等方面，且这种缺陷与额叶功能测量显著相关。在研究2中，我们发现相对于配偶对其能力的评估，PD患者高估了自己的能力，因此没有意识到自己在语用社交交流技能方面问题的严重程度。
我们得出结论，PD患者的语用社交交流技能受损，且这种受损可能与额叶功能障碍有关。
