Franke J, Runge H, Grau P, Fengler F, Wanka C, Rempel H
Acta Orthop Scand. 1976 Feb;47(1):20-7. doi: 10.3109/17453677608998967.
The bones of two patients, one with a moderate and one with a severe chronic industrial fluorosis (stage I-II and stage III), and the bones of three control persons were examined. The following parameters were determined: the fracture load, the fracture load/unit area (resistance to pressure) of the body of the first lumbar vertebra, the bending strength of the neck of the femur and of the lower third of the femur, the fracture load/unit area and the modulus of elasticity of femoral slices 2 cm thick and of precisely defined cylinders from the femoral cortex. The microhardness according to Vickers on the cross section of the femur was also determined. The results obtained are discussed with regard to fluoride therapy of osteoporosis.
对两名患者（一名患有中度慢性工业氟中毒，另一名患有重度慢性工业氟中毒，分别处于I-II期和III期）以及三名对照人员的骨骼进行了检查。测定了以下参数：第一腰椎椎体的骨折负荷、骨折负荷/单位面积（抗压强度）、股骨颈和股骨下三分之一处的抗弯强度、2厘米厚的股骨切片和取自股骨皮质的精确定义圆柱体的骨折负荷/单位面积以及弹性模量。还测定了股骨横截面上根据维氏硬度得出的显微硬度。结合骨质疏松症的氟化物疗法对所得结果进行了讨论。
