Laurenceau J L, Dumesnil J G, Gagné S
Arch Mal Coeur Vaiss. 1975 Jun;68(6):619-24.
Although echocardiography has been useful in diagnosing significant left-to-right shunts at the atrial level, few studies using this technique to quantitate shunt size have been performed. Echocardiograms and hemodynamic data from 28 patients, ages 15 to 58 (mean : 30 years) were reviewed. Twenty patients had isolated atrial septal defects (ASD), 6 patients has associated partial pulmonary venous returns (PPVR) and 2 patients had isolated PPVR. Echocardiograms in the supine position were performed within 24 hours preceding cardiac catheterization. The presence or absence of paradoxical septal motion was noted and right ventricular diameter index (RVDE : right ventricular diameter/body surface area) was calculated. Hemodynamic parameters studied included pulmonary to systemic flow ratio (Qp/Qs) determined by oxymetry, right ventricular pressure (RVP) and pulmonary resistance (PR). One patient with a Qp/Qs of 1.3 had normal septal motion. Type A paradoxical septal motion was noted in 22 cases, type B in 5 cases. For these 27 patients, the average RVDI was 2.42 (range 1.45 to 3.7), Qp/Qs ranged from 1.5 to 5 (mean : 2.45), RVP from 23 to 71 mmHg (mean : 39) and PR from 0.6 to 4 units (mean : 1.79). A very strons correlation between RVDI and Qp/Qs was observed from equation Qp/Qs : 1.19 RVDI-0.43 with a standard error of 0.4. This relationship was not altered by either RVP or PR values, which also had no apparent correlation with RVDI. This study indicates that echocardiographic measurement of RVDI is a reliable and non-invasive method of evaluating the size of left to right shunts at the atrial level.
虽然超声心动图在诊断心房水平明显的左向右分流方面很有用,但很少有研究使用该技术来定量分流大小。回顾了28例年龄在15至58岁(平均:30岁)患者的超声心动图和血流动力学数据。20例患者有孤立性房间隔缺损(ASD),6例患者合并部分肺静脉回流(PPVR),2例患者有孤立性PPVR。在心脏导管插入术前24小时内进行仰卧位超声心动图检查。记录有无矛盾性室间隔运动,并计算右心室直径指数(RVDE:右心室直径/体表面积)。研究的血流动力学参数包括通过血氧测定法确定的肺循环与体循环血流量比值(Qp/Qs)、右心室压力(RVP)和肺血管阻力(PR)。1例Qp/Qs为1.3的患者室间隔运动正常。22例出现A型矛盾性室间隔运动,5例出现B型。对于这27例患者,平均RVDE为2.42(范围1.45至3.7),Qp/Qs范围为1.5至5(平均:2.45),RVP为23至71 mmHg(平均:39),PR为0.6至4单位(平均:1.79)。从方程Qp/Qs:1.19 RVDI - 0.43观察到RVDE与Qp/Qs之间存在非常强的相关性,标准误差为0.4。这种关系不受RVP或PR值的影响,RVP和PR值与RVDE也无明显相关性。本研究表明,超声心动图测量RVDE是评估心房水平左向右分流大小的一种可靠且非侵入性的方法。